OneOhio unveils $45M grant opportunity to advance recovery and community resilience
The OneOhio Recovery Foundation has announced a new statewide grant opportunity making up to $45.7 million available to support prevention, treatment and recovery. Organizations working to address substance use disorder are invited to prepare for the upcoming Funding Inquiry window, which opens on Wednesday, Jan. 14. The full Regional Grant Cycle 2 Request for Proposals is available on the grant headquarters webpage at OneOhioFoundation.com/Grants.
“This next round of grants builds on the momentum of our first cycle and represents another powerful opportunity for Ohioans to come together and create lasting change,” said OneOhio Executive Director Alisha Nelson. “With these investments, we can expand hope, strengthen recovery, and equip local organizations with the tools they need to help more individuals and families heal.”
To support applicants throughout the grant process, the Foundation will host multiple webinars, including the first of two Grant Cycle 2 RFP Overview sessions on Dec. 16. Details about all upcoming events will be posted on the Foundation’s website.
Among key dates for applicants to consider:
• December 10, 2025: Regional Grant Cycle 2 RFP posted
• January 14, 2026: Regional Grant Cycle 2 Funding Inquiry window opens
• February 11, 2026: Regional Grant Cycle 2 Funding Inquiry window closes.
This new round of grants builds on the success of Regional Grant Cycle 1, during which the Foundation awarded more than $45 million to over 240 projects across Ohio. That process was locally driven, rigorously reviewed, and focused on evidence-informed approaches that addressed substance use disorder from multiple angles. Funded projects ranged from youth prevention initiatives and school-based mental health supports to recovery housing, treatment expansion, post-overdose outreach, and workforce development for the behavioral health field.
The Foundation continues to work closely with its 19 Regions to ensure funding decisions reflect local priorities and community needs. Drawing on lessons learned from the first round, including extensive feedback from regional partners, the Foundation has refined several aspects of its process to streamline the applicant experience while maintaining a strong commitment to transparency and accountability.
With the launch of Regional Grant Cycle 2, the Foundation continues its stewardship of Ohio’s opioid settlement resources, ensuring they are invested responsibly and strategically to create measurable, long-term impact. OneOhio remains dedicated to fostering solutions that support Ohioans impacted by addiction epidemic, empower communities, and advance recovery across the state.
For more information or to sign up for updates, visit OneOhioFoundation.com/Grants.
The OneOhio Recovery Foundation is a nonprofit charitable foundation created under the leadership of Governor Mike DeWine and Attorney General Dave Yost, and other state and local leaders, with the mission advancing Ohio’s addiction prevention, treatment, and recovery efforts now and into the future.
The Foundation is governed by a 29-member board from across Ohio and is funded by 55 percent of settlement funds that Ohio is receiving from the pharmaceutical industry as a consequence of its role in the national opioid epidemic. Funds support efforts to prevent and combat addiction and are also invested to support those efforts for the long term. Visit OneOhioFoundation.com for more information.